Two sample MR report
ERAP2_Dendritic Cell (DC) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 10 | -0.0758239 | 0.1484236 | 0.6232437 |
| Weighted median | 10 | -0.0599913 | 0.0199963 | 0.0026987 |
| Inverse variance weighted | 10 | -0.0545933 | 0.0154794 | 0.0004206 |
| Simple mode | 10 | -0.0638160 | 0.0282943 | 0.0505521 |
| Weighted mode | 10 | -0.0632972 | 0.0283322 | 0.0523444 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.904565 | 8 | 0.9837991 |
| Inverse variance weighted | 1.925251 | 9 | 0.9925952 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0138716 | 0.0964479 | 0.8891954 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003614 | 0 | TRUE | 0.0708489 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
